5 Most Common Mistakes After Knee Replacement Surgery, According to an Orthopedic Surgeon

Dr. Patricia Varacallo, DO

By Dr. Patricia Varacallo, DO

Published on Sep. 01, 2025

If you're among the 700,000 Americans undergoing knee replacement, a leading orthopedic surgeon says protecting your new joint starts before surgery.

About the expert

  • Matthew A. Varacallo, MD, MBA, FAAOS, is a board-certified orthopedic surgeon and fellow of the American Academy of Orthopaedic Surgeons. Dr. Varacallo serves as Director of Orthopedic Robotic Surgery at Penn Highlands Healthcare in DuBois, Pennsylvania. He specializes in sports medicine and joint reconstruction, with advanced training from the University of Kentucky. He treats athletes and patients nationally and internationally, focusing on restoring mobility and helping individuals return to active lifestyles. Since 2015, Dr. Varacallo has written or been featured in more than 250 publications on orthopedics and sports medicine, joint reconstruction, anatomy, hand and upper extremity, and orthopedic education. In 2020, he was named one of Becker’s “Top 65 Total Knee Replacement Surgeons To Know.”

Highlights

  • Knee replacements are among the most common orthopedic surgeries in the U.S.
  • Many people are surprised to learn that mistakes affecting recovery often start before surgery.
  • Recovery is a step-by-step process that requires preparation, patience, and follow-through.
  • An orthopedic surgeon shares how to avoid the top five mistakes after knee replacement surgery and set yourself up for long-term success.

Each year, more than 700,000 Americans undergo a total knee replacement, according to the American Academy of Orthopaedic Surgeons (AAOS), making it one of the most common orthopedic surgeries performed today. With large segments of the population getting older as Baby Boomers age and Americans staying active later in life—and, as surgical advancements make recovery gentler on average—Americans are increasingly turning to joint replacement as a solution for chronic pain. As more consider the procedure, the desire to understand recovery makes sense.

A knee replacement involves removing damaged bone and cartilage and replacing them with an artificial joint made of metal and plastic. Depending on your condition, your surgeon may recommend a total knee replacement, where the entire joint is replaced, or a partial knee replacement, which targets only the damaged section.

While the surgery is highly effective for treating severe arthritis, joint deformities, and long-standing pain, success depends on more than just the operation itself. “When it comes to getting ready for knee replacement surgery, it is critical to get your mind and body ready to have a successful outcome,” says Matthew Varacallo, MD, MBA, FAAOS, board-certified orthopedic surgeon and director of orthopedic robotic surgery at Penn Highlands Healthcare in DuBois, Pennsylvania.

Preparing in advance—through healthy eating, weight management, and pre-surgery exercise—can set you up for the best possible recovery, he adds. “Healthy patients heal faster,” Dr. Varacallo says, but adds: “Do not become discouraged if you have medical conditions that need management by your primary care doctor or specialists.” He notes that factors such as obesity, diabetes, poor nutrition, or tobacco use can increase the risk of surgical issues. “Some surgeons will require a pre-operative dental clearance prior to knee replacement surgery. It is important to discuss these with your care team regarding getting optimized leading up to your surgery.”

With that foundation in place, Dr. Varacallo says the following are common mistakes after knee replacement surgery. Navigate these to set yourself up for a smoother, successful recovery.

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knee surgery patient with mesh bandage walking with orthopedic walker
Willowpix/Getty Images

The top 5 mistakes after knee replacement surgery

Mistake 1: Unrealistic expectations for healing

Recovery after knee replacement takes time, and rushing the process can set you back.

“Recovery timelines vary significantly among patients and depend on several individual factors,” says Dr. Varacallo. Patients with severe arthritis (“bone on bone”), deformities (“bowed” or “knock-kneed”), or joint stiffness often experience longer recovery periods. Delaying surgery for too long can also make recovery harder. “Make sure to ask and discuss this with your surgeon regarding the current state of your knee so that you may have realistic expectations for your recovery timeline and outlook.”

Dr. Varacallo shares what recovery often looks like these days:

  • Walking with physical therapy the same day as surgery
  • Daily exercises in the hospital or at home
  • Using a cane or walker for two to four weeks, then gradually transitioning to normal walking
  • Driving again within two to four weeks (start by practicing in a parking lot)
  • Returning to sedentary work within weeks, or three to four months for more physically demanding jobs
  • Steady improvement over the first six months, with progress continuing up to one to two years

To help patients get the best results, many orthopedic surgeons, including Dr. Varacallo, now use robotic-assisted surgery. “I regularly utilize robotic-assisted surgery, which provides more precise and accurate joint preparation, improving the overall alignment and stability of the knee implant,” he says. This technology, combined with good strength and flexibility going into surgery, can support a faster recovery and smoother movement after the operation.

“While it is natural to want to return quickly to your regular routine, carefully following the instructions from your surgeon, healthcare providers, and physical therapist is essential,” Dr. Varacallo says. “Do not hesitate to ask for assistance with daily tasks. Having support from a family member, friend, or neighbor can be particularly important during the first two weeks after surgery.”

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physiotherapist working with knee surgery patient
Javier Zayas Photography/Getty Images

Mistake 2: Skipping exercises

Exercise is one of the most important parts of recovery, yet it’s also one of the most commonly overlooked. Shortly after surgery, you’ll begin gentle movements to keep your joint flexible and prevent blood clots. Dr. Varacallo recommends exercises such as:

  • Ankle pumps
  • Quad sets
  • Heel slides
  • Straight leg raises

As you progress, additional exercises help restore range of motion and strength:

  • Knee extension stretches
  • Seated and standing knee bends
  • Short arc quads
  • Small step-ups

By one to two months, focus shifts to rebuilding strength and endurance with:

“Remember, your body and joints work together,” Dr. Varacallo says. Exercises after knee replacement often target the hip, core, and lower back muscles to enhance your overall function as you continue recovering.” His advice: take it step by step. “Avoid rushing into advanced movements before comfortably mastering foundational exercises early in your recovery.”

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close up of person holding knee due to pain
kieferpix/Getty Images

Mistake 3: Ignoring pain or swelling

“Experiencing some degree of pain and swelling after surgery is normal and expected,” says Dr. Varacallo. But brushing these symptoms off, or not managing them properly, can slow your healing.

Here’s a general timeline of what many patients can expect:

Weeks one to two: Pain is most noticeable and may require medication.
Weeks three to six: Pain transitions from surgical discomfort to soreness from rehab exercises.
Beyond six weeks: Pain should be mild and mostly linked to activity.

“During the first two weeks after your surgery you should be using ice packets, ice machines, or cold compression devices roughly every two to three hours, for 15 to 20 minutes at a time,” Dr. Varacallo says. “It is important to ice immediately after physical therapy or exercise to reduce inflammation.”

As healing continues, icing should remain part of your routine. Between weeks three to six, Dr. Varacallo recommends icing three to four times per day, especially after activity. Each session should last 15 to 20 minutes, but can extend up to 30 minutes if swelling persists. A helpful tip is to ice before bed to reduce overnight swelling.

Beyond six weeks, icing once or twice daily after activity may still be helpful. Always monitor your pain levels and reach out to your care team if you notice issues such as:

  • Pain not relieved by medication
  • Sudden worsening pain
  • Sharp, burning, or prolonged pain with redness or warmth
  • Pain with numbness or tingling in the leg
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medical bandage on bright blue background
detkov dmitrii/Getty Images

Mistake 4: Neglecting wound care and medication

Caring for your surgical site and following your medication plan are essential steps to prevent complications and support healing.

When it comes to wound care, always follow your surgeon’s instructions. “The frequency of dressing changes depends on your surgeon’s preferences and the type of skin closure used (staples or surgical glue),” Dr. Varacallo says. “If the surgical site is bleeding and saturating the bandage, it can be changed, but a general guideline is if the site is covered and dry for the first week, then any bandages can be removed thereafter.”

Medication management typically includes:

  • Pain control: Opioids like oxycodone or tramadol may be prescribed for the first week or two, but they should be tapered quickly to avoid dependence. Because constipation is a common side effect, these medications are usually paired with a stool softener.
  • Over-the-counter options: As pain improves, most patients switch to medications like Tylenol.
  • Blood thinners: Drugs such as aspirin, Eliquis, or Xarelto are often prescribed for two to six weeks to reduce the risk of blood clots.
  • Antibiotics: These are given through an IV before and after surgery, and in some cases your surgeon may prescribe oral antibiotics for several days post-surgery.
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doctor examining patient
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Mistake 5: Not following your doctor’s advice

One of the most important parts of recovery is sticking to your care plan after surgery. Skipping follow-ups or ignoring your provider’s instructions can put your healing at risk.

The schedule for post-op visits may vary by surgeon, but generally includes check-ins at:

  • Two weeks after surgery
  • Six weeks
  • Three months
  • Six to 12 months

These visits allow your surgical team to monitor your progress, address concerns, and adjust your recovery plan as needed. Appointments may be with your surgeon or with trained members of the care team, such as nurse practitioners or physician assistants.

“I always tell my patients that a successful surgery truly is a partnership between the providers and patients,” says Dr. Varacallo. “Staying motivated, proactive, maintaining a positive outlook, and closely following your healthcare team’s instructions will significantly improve your chances of achieving an excellent outcome.”

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