Health News: Creepy Creatures Fight Disease, Infection and More
Sometimes the most innovative medical treatments come from the grossest of creatures.
Moths: An Allergy-Free Flu Vaccine
Flu vaccines are typically produced by growing influenza virus inside chicken eggs, which means people with egg allergies may develop a serious reaction. A newly FDA-approved vaccine, Flublok, avoids this risk by replicating the virus in cells derived from the fall armyworm moth. The method has been used for other vaccines but not for flu until now. What’s more, it allows for much quicker vaccine production, which will make more doses available sooner if there’s ever a flu pandemic. The new vaccine will be ready for the upcoming flu season.
Source: Manon Cox, PhD, president and CEO, Protein Sciences Corp., Meriden, Connecticut
Frogs: Fight Infections
Scientists are hoping to develop new drugs
from the skin of the Russian brown frog after discovering that it
secretes antimicrobial goo. Since many frogs live in dank, wet places
teeming with germs, their skin must serve as armor against these
microscopic threats, scientists theorized. When Moscow State University
researchers extracted the goo from living frogs, they found 76 new
chemicals with antibacterial and antifungal properties—some as powerful
as prescription antibiotics. Researchers plan to collaborate with
pharmaceutical companies to synthetically produce these substances.
Source: Albert T. Lebedev, PhD, Department of Organic Chemistry, Moscow State University
Scorpions: Crush Cancer
Scorpion venom may serve a surprisingly beneficial purpose: helping brain surgeons excise malignant tissue easily and accurately. Researchers at the Fred Hutchinson Cancer Research Center, Seattle Children’s Hospital Research
Institute, and the University of Washington combined an extract of
scorpion venom that naturally (and safely) targets only cancer cells with a molecule that glows under a special light. During surgery for brain tumors,
doctors could inject the substance, spot glowing cancerous tissue, and
remove every last millimeter of it, leaving only healthy tissue behind.
Early studies suggest that the chemical could also illuminate prostate, breast,
colon, and some skin cancers. Researchers have used the technique to
treat cancer in animals; human trials are planned for the end of this
Source: Jim Olson, MD, PhD, Fred Hutchinson Cancer Research Center, Seattle, Washington
Mussels: Manage Toothaches
Some tooth pain develops when the hard outer enamel wears away and exposes the
softer underlying dentin, which is sensitive to stimuli such as hot and
cold. Pain-fighting toothpastes and chewing gums contain minerals that
can augment enamel but don’t adhere long enough to permanently rebuild
it. For a solution, Chinese scientists turned to mussels, which secrete
an adhesive to attach to underwater rocks, and they created a
substance with similar sticky properties. When scientists coated
worn-out teeth with the mussel-like adhesive and then soaked them in a
bath of minerals, the teeth rebuilt a protective layer that simulates
enamel. The discovery could lead to better products for sensitive teeth.
Source: ACS Applied Materials & Interfaces; Chun Hung Chu, PhD, University of Hong Kong; and Quan-Li Li, Anhui Medical University, China