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The Most Popular Weight-Loss Products on Amazon

We checked out the top-selling and most popular weight-loss products on Amazon to figure out exactly how they work and who they're best for.

Every editorial product is independently selected, though we may be compensated or receive an affiliate commission if you buy something through our links.

Havasu Nutrition Extra Strength Apple Cider Vinegar Pills via amazon.com

Apple cider vinegar pills

By now, we’ve all heard that apple cider vinegar, or ACV, is a wonder-cure for just about everything. But how does it work, and why are these Havasu Nutrition Extra Strength apple cider vinegar pills the most popular weight-loss pills on Amazon right now? It turns out these pills may help you avoid storing fat, but only if you’re already eating a reduced calorie diet and exercising.

“Acetic acid is the main component of vinegar and gives it that memorable taste. It has been shown in multiple scientific studies to suppress the ability of the body to store fat,” explains Ryan Neinstein, MD, a New York plastic surgeon. “In addition to the control of daily calorie intake and a more active lifestyle, consuming diets or food with bioactive nutrients has been proposed as an effective solution to combat and even prevent obesity.”

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Garcinia Cambogia 100% Pure Garcinia Cambogia Extract with HCA, Extra Strengthvia amazon.com

Garcinia cambogia

Have you been seeing ads for this appetite suppressant pop up all over your internet browser? You’re not alone, and it’s because it’s one of the most popular weight-loss supplements of the moment. This 100% Pure Garcinia Cambogia Extract with HCA in Extra Strength is one of Amazon’s best-sellers, as it’s easy to use and inexpensive. However, it’s not for people who are pregnant, nursing, or allergic to rice bran, according to the label.

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BURN-XT Thermogenic Fat Burner - Weight Loss Supplement, Appetite Suppressant, Energy Booster via amazon.com

BURN-XT Thermogenic Fat Burner

This is one of the more intense additions to our list of popular weight-loss supplements on Amazon, thanks to the formula’s variety of fat burners and appetite suppressants including Acetyl L-Carnitine HCL, green tea leaf extract, caffeine, cayenne pepper fruit extract, and other known metabolism enhancers. The caffeine in BURN-XT Thermogenic Fat Burner may give you the jitters, though, so this one should be taken with caution.

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alli Diet Pills for Weight Loss, Orlistat 60 mg Capsules, Refill Pack 120 count via amazon.com

alli

This popular diet pills have been on the market for years and remain a crowd favorite. The brand alli is just one variety of orlistat, the official drug name. “Orlistat blocks the breakdown of fat which reduces fat absorption from intestines,” explains Dr. Neinstein. “The drug is well tolerated and safe,” he says, “but can have some gastrointestinal side effects like an upset stomach and frequent trips to the bathroom.” Read up on 38 fat-burning foods that can help you lose weight.

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Atkins Gluten Free Protein-Rich Shake, Milk Chocolate Delight, 12 Countvia amazon.com

Gluten-free protein shakes

It’s no surprise that Atkins gluten free protein-rich shakes are near the top of this list. The low-carb Atkins diet has been popular for decades; it emphasizes a high protein, high fiber, carb-avoidance approach. These meal replacement shakes offer just that, and you don’t have to think too hard.

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NatureWise CLA 1250, High Potency, Natural Weight Loss Exercise Enhancement, Increase Lean Muscle Mass, Non-Stimulating, Non-GMO, Gluten-Free, 100% Safflower Oil, 90 count via amazon.com

NatureWise CLA 1250

If you haven’t already heard of CLA supplements, allow us to introduce you to a relatively new weight loss craze. Conjugated linoleic acid—CLA—is a naturally occurring polyunsaturated fatty acid that we consume in dairy and beef and is thought to play a role in breaking down fats, according to the National Institutes of Health. The science on the substance is mixed, but that hasn’t stopped NatureWise CLA 1250 from nearly topping the list of the most popular weight-loss products on Amazon.

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Zero Tea 14 Day Detox Tea, Weight Loss Tea, Teatox Herbal Tea for Cleanse via amazon.com

Detox teas

Instagrammers know that detox teas are just about everywhere right now, and Zero Tea 14 Day Detox Tea is the most popular version on Amazon. The tea claims to boost your metabolism by clearing out bacteria like Candida which can leave you feeling sluggish, plus stimulating a more thorough “cleanse” of your digestive tract. While you may not lose much in the way of fat, you’ll likely end up feeling a lot less bloated.

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SlimFast Advanced Nutrition Creamy Chocolate Shake – Meal Replacement – 20g of Protein – 11oz – 12 Count via amazon.com

SlimFast shakes

Did SlimFast ever really lose steam? We don’t think so, and these protein-rich shakes have been a favorite low carb staple of dieters around the country for years. The SlimFast chocolate flavor seems to be especially popular—throw in a banana, some blackberries, or even a scoop of fiber powder for a whole new take on an old classic. Here are 13 things experts wish you knew about losing weight.

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Keto Pills - Weight Loss Supplements to Burn Fat Fast - Boost Energy and Metabolism - Best Ketosis Supplement for Women and Men - Best Keto Diet - 60 Capsules via amazon.com

Keto Pills

The ketogenic diet is one of this year’s most popular. It’s essentially a much more aggressive spin on the low carb diet you’ve been hearing about for years. The Keto Pills are said to help your body reach fat-burning ketosis faster, which is the ultimate goal of every ketogenic dieter. Here’s a Keto Diet menu to follow for beginners.

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Pure Garcinia Cambogia Extract - 95% HCA Capsules - Best Weight Loss Supplement - Non GMO - Gluten & Gelatin Free - Natural Appetite Suppressant - 100% Money Back Guarantee - Order... via amazon.com

Gelatin-free garcinia cambogia extract

Yet another garcinia cambogia product made our list of the most popular weight-loss supplements on Amazon, and this one is gelatin-free. That means this bottle of Pure Garcinia Cambogia Extract pills is ideal for vegetarians. This is the only crash diet you should ever consider if you need to lose weight fast.

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Aerobic Life Mag O7 Oxygen Digestive System Cleanser Capsules, 90 Countvia amazon.com

Digestive system cleansing capsules

Similar to the concept of detox teas, Aerobic Life Mag O7 Oxygen Digestive System Cleanser capsules have become a fast-rising diet star on Amazon. The main difference, however, is that this formula uses a combination of magnesium oxide compounds to release gradually over 12 or more hours, helping kill off harmful bacteria populations, according to a 2018 study in the journal Nature, and encourage positive probiotic growth.

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100% Pure Garcinia Cambogia Extract 95% HCA, 2100 mg Capsules | Appetite Suppressant | Non-Stimulating | Weight Loss Pills, Burn Fat & Boost Metabolism, Highest Potency Diet... via amazon.com

Even more garcinia cambogia

Seriously, garcinia cambogia is extraordinarily popular, and this 100% Pure Garcinia Cambogia Extract 95% HCA variety is no exception. It’s slightly less expensive than some of the other versions out there and offers 90 capsules per bottle. Also check out these 50 easy ways to lose weight naturally.

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Skinny Gal Weight Loss for Women, Diet Pills by Rockstar, The #1 Thermogenic Diet Pill and Fast Fat Burner, Carb Block & Appetite Suppressant, Weight Loss Pills, 60 Veggie Cap via amazon.com

Skinny Gal Weight Loss for Women pills

The name really says it all, and this weight-loss supplement for women is one of the most popular on Amazon because it claims to suppress appetite, boost energy, and block carbs. The Skinny Gal Weight Loss for Women formula includes raspberry ketones, African mango extract, and the omnipresent garcinia cambogia. Here’s what you need to know about gardenia cambogia.

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Hydroxycut Hardcore Elite , 100ct, 100mg Coleus Forskohlii, 56.3mg Yohimbe, 200mg Green Coffee, 100mg L-Theanin ,200mg C.canephora Robusta (Packaging May Vary) via amazon.com

Hydroxycut

Hydroxycut’s newer lineup includes their Hydroxycut Hardcore Elite formula, which is loaded with appetite-suppressing stimulants and energy boosters to keep you in the mood to be active and less inclined to eat. It’s definitely not a good choice for those who are pregnant, nursing, or with a history of heart or blood pressure issues, according to the label. Read up on these 15 bad weight-loss tips doctors wish you’d stop following.

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LEAN PM Night Time Fat Burner, Sleep Aid Supplement, & Appetite Suppressant for Men and Women - 60 Stimulant-Free Veggie Weight Loss Diet Pills via amazon.com

Sleep-ready fat burners

The new wave of fat-burning supplements is the exact opposite of the last, and these are meant to help you while you’re as inactive as can be—during your sleeping hours. LEAN PM Night Time Fat Burner has risen in Amazon fame, combining powerful fat-burning ingredients with sleep enhancers. The formula claims to be stimulant-free and packed with melatonin and vitamin B6 to help lull you into a fat-burning sleep trance.

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100% Natural Raw Apple Cider Vinegar Pills (1500 mg | 120 Capsules) Pure Apple Cider Vinegar with Cayenne Pepper for Fast Weight Loss Cleanse, Appetite Suppressant, & Bloating Reliefvia amazon.com

More apple cider vinegar pills

Apple cider vinegar is a non-stop dieting win for Amazon shoppers, which is why these Zeal Naturals 100% natural raw apple cider vinegar pills made our top 25 list as well. Here’s how apple cider vinegar works for weight loss.

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Evlution Nutrition Lean Mode Stimulant-Free Weight Loss Support with Garcinia Cambogia, Carnitine, CLA, and Green Tea Leaf extract (50 Servings) via amazon.com

Evlution Nutrition Lean Mode

This relative new-comer in the diet supplement world offers a combination of garcinia cambogia, carnitine, CLA, and green tea leaf extract in a stimulant-free formula that’s meant to be ideal for people who don’t tolerate caffeine particularly well. Here are more of the best vitamins and supplements for weight loss.

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SlimFast – Original Meal Replacement Shake Mix Powder – Weight Loss Shake – 10g of Protein – 24 Vitamins and Minerals Per Serving – Great Taste – 31.18 oz. – Rich Chocolate Royale Flavor via amazon.com

Protein powders

While protein powders and mixes are growing in acceptance, the most popular one on Amazon is still SlimFast original meal replacement shake mix powder. You can whip it up with water and ice in a blender as directed, or get creative by adding some blueberries, raspberries, or other fruits in for flair.

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Colon Cleanser & Detox for Weight Loss. 15 Day Extra Strength Detox Cleanse with Probiotic for Constipation Relief. Pure Colon Detox Pills for Men & Women. Flush Toxins, Boost Energy. Safe & Effective via amazon.com

Colon cleansing systems with probiotics

Why stop at two weeks when you can give yourself a full 15 days? That’s exactly the concept behind BioSchwartz Colon Cleanser & Detox. Each pill contains billions of units of active probiotics, several types of herbs, and no fillers or binders. The idea is that you’ll flush out stored waste and toxins over the course of a 15-day treatment cycle, leaving you with a flatter belly and more energy. Here are more of the best probiotics for weight loss.

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VINTAGE BURN Fat Burner - The First Muscle-Preserving Fat Burner Thermogenic Weight Loss Supplement – Keto Friendly - For Men and Women - 120 Natural Veggie Pills via amazon.com

Vintage Burn Fat Burner

Aside from the kitschy name and late 1970s-style packaging, this weight-loss supplement promises a powerful punch with thermogenic ingredients. While the label suggests that the formula is for both men and women, it’s not safe for pregnant or nursing women.

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Vega One Organic All-in-One Shake Chocolate (17 servings, 1.6 lb) - Plant Based Vegan Protein Powder, Non Dairy, Gluten Free, Non GMO via amazon.com

Vega One Organic All-in-One Shake

Think of this protein and fiber drink as the meal replacement shake of the modern era. Vega One Organic All-in-One Shake in chocolate is a best-seller thanks to a plant-based, vegan formula that boasts absolutely no dairy, gluten, or GMOs. It’s ideal for those with rigid dietary restrictions and lactose sensitivities. If you like this, you should check out these other things nutritionists buy on Amazon.

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NOW Apple Cider Vinegar 450 mg,180 Capsules via amazon.com

Lower dose apple cider vinegar capsules

If you’re just getting into apple cider vinegar as a weight-loss supplement, starting at a lower dose may be a good idea, which is why NOW apple cider vinegar 450 mg capsules are high on Amazon’s list of popular supplements. They’re very inexpensive compared to other brands as well. Learn some more amazing health benefits of taking apple cider vinegar.

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(2 Pack) Apple Cider Vinegar Pills w/Garcinia Cambogia (1500mg | 180 Capsules) Appetite Suppressant Natural Weight Loss Diet - Detox Cleanse, Lose Weight Fast Bloating Relief Dietary Supplement via amazon.com

Apple cider vinegar pills with garcinia cambogia

Doubling up these fat burning and appetite suppressing supplements may help boost your weight-loss efforts, which is why Mix Rx apple cider vinegar pills with Garcinia cambogia is a popular choice. Make sure you avoid these 13 weight-loss products nutritionists never buy.

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Forskolin Extract for Weight Loss. Pure Forskolin Diet Pills & Belly Buster Supplement. Premium Appetite Suppressant, Metabolism Booster, Carb Blocker & Fat Burner for Women and Men Coleus... via amazon.com

Forskolin extract

This is the first forskolin supplement on our list, but we won’t be shocked if forskolin grows in overall popularity in coming months—the traditional herbal medicine is getting a lot of press as an extreme appetite suppressant and carb-blocker for those wishing to head into ketosis faster. BioSchwartz Maximum Strength Forskolin Extract is the top-seller on Amazon right now in this category.

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Vitamin Bounty - Forskolin 500mg - 60ct via amazon.com

Budget-friendlier forskolin

If you’re looking to try forskolin extract (which comes from a tropical plant related to mint) without dropping quite as much cash, you can ease into a lower-dose supplement at a reduced price, like this extremely popular bottle of Vitamin Bounty Forskolin 500 mg. It’s made in the USA, it’s thought to improve overall metabolism, and some studies claim it positively impacts blood pressure levels. Next, don’t miss these 50 simple ways to boost your metabolism.

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Bryce Gruber
Bryce Gruber is Editor of The Luxury Spot, a lover of gift and travel guides, and frequently appears on TV talking about products and travel—when she's not trying to get her five kids to eat their vegetables. She lives, works, and plays with her husband in New York City, because where else? Find her on social media at @brycegruber. She's everywhere.