Whatโs in a blood type?
Potentially a lot, according toย research, including a review of studies published in the Wiley Interdisciplinary Reviews: Systems Biology and Medicine,ย that correlates different blood groups to everything from risk of heart disease and dementia to urinary tract infections and the norovirus. While none of the studies are conclusive about cause and effect (they canโt say X blood type causes Y disease) and any increased risks are still pretty small, the research does highlight the importance of knowing your typeโA, B, AB, or Oโand how it could affect your well-being. Plus, here’s the real reason blood is red.
Blood clots: Type AB, A, and B increases risk
Danish researchers studied how blood type interacts with a genetic predisposition for deep-vein thrombosis (DVT), or blood clots in the lower legs that can travel to the lungs and become life-threatening. After analyzing data on about 66,000 people over more than 30 years, they found that those with type AB, A, or B had a 40 percent higher risk of DVT than people with type O, the most common type.
When the scientists did further analysis to see which factors have the biggest impact on DVT risk on a population level, they found that an AB blood type contributed to about 20 percent of blood clots; genetic mutations accounted for 11 percent, being overweight accounted for 16 percent, and smoking accounted for 6 percent.ย Here are the blood clot symptoms you should definitely not ignore.
Heart disease: Type AB, B, and A all increase risk
People whose blood type is A, B, or AB have an increased risk of heart disease and shorter life spans than people who have type O blood, according to a large study published inย BMC Medicine. After following more than 50,000 middle-age and elderly people for seven years, on average, researchers found that as many as 9 percent of cardiovascular deaths were attributed to having non-O blood types.ย However, as any doctor will tell you, lifestyle factors like weight, smoking, and diet, which, unlike blood type, are modifiable, have a much greater impact on heart disease. Learn how men with this blood type could be more likely to have a heart attack.
Stomach Cancer: Types A and AB increases risk
Fertility: Type O reduces it
Women with this blood type were twice as likely to have blood levels of the hormone FSH high enough to indicate low ovarian reserve, a measure of fertility, according to a study published in Human Reproduction. Researchers couldnโt say for sure why, though. Given that type O blood is the most prevalent across all U.S. ethnicities, it doesnโt pay to worry too much about it. Age is a far more important risk factor for fertility problems. Here are some more surprising facts about fertility.
Pregnancy risks
This has nothing to do with your “letter” blood type or the type determined by the ABO grouping system. This has to do with what’s known as the Rhesus (Rh) factor, which determines whether your blood type is positive or negative. This could cause complications in pregnant women if the baby’s Rh blood type is different from the mother’s. For instance, if the mother has a negativeย blood type and the baby has a positiveย one, the mother’s body can actually build up antibodies against the baby’s blood type. Luckily, this doesn’t affect the baby, but it could have a negative effect on future pregnancies. Fortunately, doctors can give pregnant women a shot early in their pregnancy that can prevent Rh-incompatibility problems. Learn why parents-to-be need vaccinations just as much as babies do.
Dementia and memory loss: Type AB increases risk
People with type AB blood have an 82 percent greater risk for cognitive decline later in life, according to aย study published inย Neurology. Study participants with higher levels of the Factor VIII protein, which helps with blood clotting, were 24 percent more likely to develop memory problemsโregardless of their blood typeโthan people with lower levels. Blood type, however, is far from theย only,ย or even most important,ย factor that affects your risk for cognitive decline. High blood pressure, diabetes, and smokingย all increase your risk for dementia.
Stroke: Type O has the lowest risk
People with type AB have a higher risk of cardiovascular issues such as stroke, according to a study published in the Journal of Thrombosis and Haemostasis. Biologists are still investigating why this might be; one possible explanation is that non-O blood types contain more of the Von Willebrand factor, a protein that has been connected to blood clotting and stroke in the past.
Mosquitoes like Type O blood
If you find yourself scratching bug bites all summer long, your blood type might be to blame. In a one small study, researchers found thatย type Os are up toย twiceย as attractive to mosquitoes as type As, with type Bs falling somewhere in the middle. Here are some more reasons you’re being bitten by mosquitoes (some of which you actually can control).
- Wiley Interdisciplinary Reviews: Systems Biology and Medicine, "Blood Type Biochemistry and Human Disease"
- Journal of Thrombosis and Haemostasis: "ABO blood groups and risk of venous thromboembolism during pregnancy and the puerperium. A populationโbased, nested caseโcontrol study"
- Journal of Internal Medicine,ย "Acute infections and venous thromboembolism"
- BMC Medicine, "Mortality and cancer in relation to ABO blood group phenotypes in the Golestan Cohort Study"
- BMC Cancer, "Blood groups A and AB are associated with increased gastric cancer risk: evidence from a large genetic study and systematic review"
- Human Reproduction, "Implications of blood type for ovarian reserve"
- Mayo Clinic, "Rh factor blood test"
- Neurology, "ABO blood type, factor VIII, and incident cognitive impairment in the REGARDS cohort."
- Journal of Thrombosis and Haemostasis, "ABO Blood Type and Stroke Risk: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study"
- Journal of Medical Entomology: "Landing Preference of Aedes albopictus (Diptera: Culicidae) on Human Skin Among ABO Blood Groups, Secretors or Nonsecretors, and ABH Antigens"