12 Signs of Hashimoto’s Disease Everyone Should Know

Updated: Sep. 21, 2022

In Hashimoto's disease, the same immune system you depend on to fight infection turns on you, producing antibodies that attack your thyroid gland. Here's what you have to watch for.

Know the risk factors

Hashimoto’s disease is an autoimmune condition, where the immune system—which normally helps fight infection and disease—instead produces antibodies that attack the thyroid gland. Why a person develops Hashimoto’s disease is still a mystery, but there are a number of factors that can contribute to your risk. “If you are female, have a family history of Hashimoto’s disease or have had another autoimmune disease, you are at a higher risk for developing the disease,” says Stephanie Lee, MD, PhD, associate chief, section of Endocrinology, Nutrition, and Diabetes at Boston Medical Center.

The condition is eight times more common in women than men, and is most often diagnosed between the ages of 40 to 60 (although teens and young women can get it too), according to the National Institute of Diabetes and Digestive and Kidney Disease. About 14 million people in the U.S. have the condition.

Here are the symptoms of Hashimoto’s disease.

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A senior woman touching her neck
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Your neck is swelling

The thyroid is a butterfly-shaped gland that’s in your neck, just south of your Adam’s apple. It produces hormones that help regulate your brain, heart, metabolism, muscles and organs. If you have Hashimoto’s disease, you can develop a goiter, which is an enlarged thyroid gland. However, goiters can be caused by other things too. The most common cause of goiter around the world is an iodine deficiency, which generally isn’t a problem in the U.S., according to the American Thyroid Association. (Goiters were more common in the U.S. before iodine was routinely added to table salt, starting about 100 years ago.) However, a goiter can also indicate that you have an autoimmune disease such as Hashimoto’s disease, which is also known as Hashimoto’s thyroiditis.

13 Thyroid Symptoms to Watch Out For

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Your hair is thinning

The Mayo Clinic notes that women are much more likely to develop Hashimoto’s disease, most commonly during middle age. Though losing hair volume can be a natural part of aging, thinning hair is also a symptom of the condition. Consult with your doctor if you notice abnormal hair loss or major changes in hair thickness, especially if you also have other symptoms.


You’re exhausted

“Fatigue is a very common symptom of Hashimoto’s disease,” says Dr. Lee. If your symptoms are more extreme than mere tiredness and especially if you have ruled out other possible causes of being tired—including sleep apnea, anemia or depression—you need to have your hormone levels tested.

13 Medical Reasons You’re Tired All the Time

Women scratch the itch with hand / arm itching / Concept with Healthcare And Medicine.

Your skin is dry

As with many of Hashimoto’s disease symptoms, dry skin can be caused by a lot of conditions—eczema, psoriasis, allergies and dehydration among them. But if your skin is getting drier and you have several other symptoms on this list—or a family history of autoimmune diseases—you should talk with your doctor.

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You’re gaining weight for no good reason

Because your thyroid controls your metabolism, people with Hashimoto’s often experience unexpected weight gain. “Weight gain is also tied to getting older,” says Dr. Lee who notes that the condition often starts in middle age. “It is a shame not to diagnose Hashimoto’s early as the treatment is so easy,” says Dr. Lee. Working with an endocrinologist who is familiar with your specific case is a good idea as they can become familiar with your personal history and medical care.

Young african woman sleeping in her bed at night, she is resting with eyes closed

You experience eyelid swelling

Again, allergies and dry eyes can lead to swelling—but, says Dr. Lee, if you have this in combo with other Hashimoto’s disease symptoms, discuss the issue with your doctor.

8 Health Problems You Can Totally Blame on Your Thyroid

scanning of a thyroid of man

Your thyroid hormones are out of whack

People who have symptoms of Hashimoto’s disease will likely be screened first with a test of their thyroid-stimulating hormone (TSH) levels. “This is the primary test for hypothyroidism,” notes Elizabeth Pearce, MD, an endocrinologist at Boston Medical Center and president of the American Thyroid Association. TSH is a signal from the pituitary gland in the brain to the thyroid that says “we’re running low; make more.” When TSH is high, it can be an indicator that production is low. Most endocrinologists will do further testing on anyone with levels higher than the upper level of normal, especially in the presence of multiple symptoms. Measurement of free T4 can help differentiate between primary, secondary, and subclinical hypothyroidism.

Close up nurse pricking needle syringe in the arm patient drawing blood sample for blood test
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Diagnosing Hashimoto’s disease by symptoms alone is tricky

The good thing about having an early TSH screening test, says Dr. Lee, is that it allows doctors to diagnose thyroid disorders much earlier, even before you experience symptoms. “When you start seeing a constellation of symptoms, you should get screened,” says Dr. Lee. TSH blood tests can help doctors reach a diagnosis; they’ll also look for the symptoms above, along with depression, heavy periods, pale skin, increased sensitivity to cold and brain fog. Anyone with suspected Hashimoto’s disease may be given two antibody tests: anti-TPO and TgAb. Anti-TPO attacks an enzyme in the thyroid gland, called thyroid peroxidase, which is important in the production of thyroid hormones. TgAb attacks thyroglobulin, a key protein in the thyroid gland that is essential to the production of T4 and T3 thyroid hormones. It’s not essential to check these antibody tests if it won’t change management. Patients can have Hashimoto’s and not have positive antibodies and patients can have these anti-bodies but still have normal thyroid function. An endocrinologist can explain if checking these antibodies might be helpful to your case.

Should You Get Your Thyroid Hormone Levels Checked?

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Women who are pregnant need to pay special attention to symptoms

Women who are pregnant and experiencing symptoms of Hashimoto’s disease should be especially proactive about being screened. “If you have Hashimoto’s disease and learn you are pregnant, you should call your endocrinologist,” notes Dr. Pearce. This is especially important if you are on medication since your body won’t be producing enough thyroid hormones on its own; your doctor may need to boost your dose for the healthy development of your baby.

Doctor checking thyroid glands of senior woman
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There is no cure for hypothyroidism, but there is hope

Although there is no cure for hypothyroidism, it can become more or less severe over time. You may have to take medication for the rest of your life, and you’ll need to work closely with your doctor to monitor your dosage as you alternate from hypo- and hyperthyroid states. The good news is with proper medication and monitoring your symptoms should lessen and the effects of Hashimoto’s disease improve. You can learn a lot and find support from other Hashi’s patients by joining a support group, such as Stop the Thyroid Madness.

An elderly woman feels her thyroid gland.

Get educated about Hashimoto’s disease

Dr. Pearce points out that there is an abundance of information—and misinformation—online; she suggests that people talk directly with their doctors and reference the American Thyroid Association to learn more.

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